For diffuse gastric cancer (DGC), genetic testing for CDH1 should be considered in which of the following situations?
DGC is diagnosed before age 50 years without a family history.
Personal or family history of DGC and invasive ductal breast cancer, one diagosed before age 50.
2 cases of gastric cancers in the family, one confirmed before age 60.
3 confirmed cases of DGC in 1st or 2nd degree relatives independent of age.
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