Methods: check ALL you use, IF you practice FBLD (Poll Closed)

  • Affinity chromatography, capillary electrophoresis, or ultrafiltration
    3%
    22 votes

     
  • BLI (biolayer interferometry)
    1%
    9 votes

     
  • Computational screening
    8%
    55 votes

     
  • Functional screening (high concentration biochemical, FRET, cell-based, etc.)
    8%
    53 votes

     
  • ITC (isothermal titration calorimetry)
    7%
    46 votes

     
  • Literature or known fragments
    5%
    36 votes

     
  • MS (mass spectrometry)
    4%
    30 votes

     
  • MST (microscale thermophoresis)
    4%
    26 votes

     
  • NMR – ligand detected
    13%
    89 votes

     
  • NMR – protein detected
    9%
    62 votes

     
  • SPR (surface plasmon resonance)
    13%
    89 votes

     
  • Thermal shift (or DSF)
    12%
    85 votes

     
  • X-ray crystallography
    14%
    95 votes

     
  • Other
    1%
    4 votes

     

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