Why would a change in valproate formulation lead to increased serum VPA levels for Mr. G?

the release of the medication in IR formulation is not affected by gastric acid, and therefore is not affected by the surgery nor the prescribed omeprazole 78% (184 votes)

the IR formulation is always absorbed better than the ER formulation 20% (46 votes)

this is an anomaly and therefore an unusual case report 2% (4 votes)

Why would a change in valproate formulation lead to increased serum VPA levels for Mr. G?

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