How much structural information do you need to begin optimizing a fragment? (1/2)

I won't work on a project without a crystal structure 47% (64 votes)

I'll settle for an NMR-based model 16% (21 votes)

A computational model is fine 14% (19 votes)

SAR is good enough for me 23% (31 votes)

How much structural information do you need to begin optimizing a fragment? (1/2) (Poll Closed)