What is your take on Non-Inferiority drug trials ?
NIT is a first step to prove a drug's superiority . It is indeed a powerful statistical concept. Don't have a prejudiced view about NIT.
NIT has some statistical meaning .If done properly it can have an important role as a control.
NIT came into vogue primarily because many of the modern drugs were struggling to prove it's superiority over existing ones.So, it is essentially a back door entry for the potential losers . NIT should always be taken with a pinch of salt.
NIT is a real statistical joke.
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