Between A and B, I rather have B, the boldness the character of this book with your symbolic instrument focusing in boldness is more appealing than just a script for medicine!
While I like the design on cover B., the "Die Laughing" print at the bottom is confusing and hard to read.
Therefore the A cover is clearer and more readable
I get the idea of the Rx on the first cover (A), but the second (B) is much bolder, cleaner, clearer and less detailed. It jumped out at me; the first one didn't.
B is superior, in my view, because the subdued color gold looks more professional & the stethoscope appeals more to me , as opposed to what looks like a scrap of paper, common to an ordinary prescription slip. The cover text has effective punch lines and augurs well to the books reception when it goes to market. Best Wishes.
B much more eye catching and has a more playful vibe for a humorous book. Good luck!
Colors and images caught my attention immediately.
I like B. It talks to me and is more appealing. Best wishes on your book!